Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KAT7 | O95251 | 1/20 | 0.31 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938577 | 0.67 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL1724272 | 0.66 | — | — | |
| SCHEMBL88635 | 0.66 | ALDH1A1 (0.47) | ALDH1A1TDP1 | |
| SCHEMBL27627421 | 0.65 | CYP17A1 (0.38) | ALDH1A1 | |
| SCHEMBL6193220 | 0.62 | BACE1 (0.36) | ALDH1A1TDP1KAT7KAT6BKAT6A | |
| SCHEMBL4137306 | 0.62 | ALDH1A1 (0.41) | ALDH1A1TDP1 | |
| SCHEMBL11811765 | 0.62 | ENPP2 (0.44) | MAPK1 | |
| SCHEMBL840043 | 0.61 | — | — | |
| SCHEMBL12419351 | 0.60 | ALDH1A1 (0.32) | ALDH1A1KAT7KAT6BKAT6A | |
| SCHEMBL841688 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112823-A | Pesticides, miticides, insecticides, nematocides, molluscicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-05-12 | — | — | US | disclosed |
| EP-0395985-A2 | 3(2H)-pyridazinone derivatives, their preparation method and their use for combating pests | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |