SCHEMBL972037

SCHEMBL972037

CCOC(=O)c1cc(-c2ccc(S(=O)(=O)NCc3ccc(C)o3)c(OC)c2)on1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
TP53 P04637 2/20 0.61
POLB P06746 2/20 0.55
MAPK1 P28482 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.46
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
PKM P14618 1/20 0.42
ACR P10323 1/20 0.42
CLK1 P49759 1/20 0.42
CLK2 P49760 1/20 0.42
DYRK1A Q13627 1/20 0.42
CLK4 Q9HAZ1 1/20 0.42
DYRK1B Q9Y463 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL972405 0.86 KMT2A (0.59) MAPTTP53MEN1KMT2ATDP1
SCHEMBL21523720 0.77 MAPK1 (0.76) MAPTTP53POLBMAPK1MEN1
SCHEMBL31128524 0.74 MAPK1 (0.60) MAPTTP53POLBMAPK1MEN1
SCHEMBL31128523 0.74 MAPK1 (0.60) MAPTTP53POLBMAPK1MEN1
SCHEMBL2765109 0.71 MAPK1 (0.54) MAPTTP53POLBMAPK1MEN1
SCHEMBL22619744 0.70 KMT2A (0.56) MAPTPOLBMAPK1MEN1KMT2A
SCHEMBL15468398 0.70 MAPT (0.68) MAPTTP53MAPK1MEN1KMT2A
SCHEMBL29197994 0.68 ACR (0.60) MAPTTP53POLBMEN1KMT2A
SCHEMBL1686535 0.67 ACR (0.56) MAPTTP53POLBTHRBALDH1A1
SCHEMBL1686327 0.67 NOTUM (0.73) MAPTTP53POLBMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US claimed
EP-2252590-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2010-11-24 EP claimed
WO-2009101082-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO claimed
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US disclosed
EP-2252590-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2010-11-24 EP disclosed
WO-2009101082-A1 SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds STS, NAPA, NAAA MAPT 3640/4885TP53 783/4885POLB 4080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.