Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 8/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 8/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9720534 | 0.99 | TOP2A (0.44) | TOP2ATOP2BADRB2KDM4EALDH1A1 | |
| SCHEMBL9720466 | 0.92 | TOP2A (0.45) | TOP2ATOP2BADRB2KDM4EALDH1A1 | |
| SCHEMBL7862768 | 0.92 | TOP2A (0.52) | TOP2ATOP2BADRB2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9720598 | 0.92 | TOP2A (0.45) | TOP2ATOP2BADRB2KDM4EALDH1A1 | |
| SCHEMBL9720497 | 0.90 | TOP2A (0.43) | TOP2ATOP2BADRB2KDM4EALDH1A1 | |
| SCHEMBL9853309 | 0.90 | TOP2A (0.46) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL9720525 | 0.83 | ADRB2 (0.46) | TOP2ATOP2BADRB2KDM4EALDH1A1 | |
| SCHEMBL5732622 | 0.82 | ADRB2 (0.41) | TOP2ATOP2BADRB2ALDH1A1LMNA | |
| SCHEMBL9853310 | 0.82 | TOP2A (0.47) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL9720558 | 0.81 | TOP2A (0.57) | TOP2ATOP2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | claimed |
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | claimed |
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0417669-A2 | Pyridinyl-quinolone compounds, their preparation and use | STERLING WINTHROP INC. (US) | 1991-03-20 | — | — | EP | disclosed |