Pyridine

Pyridine

SCHEMBL9720602

CC(C)OC(C)C.c1ccncc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL4576547 0.80 ALDH1A1 (0.32)
Pyridine SCHEMBL3908730 0.78 TSHR (0.64) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL28134220 0.75 TSHR (0.60) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL11206494 0.75 TSHR (0.60) TSHRNAPRTTDP1GAA
Benzene SCHEMBL11827089 0.75 TSHR (0.60) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL6515981 0.75 TSHR (0.60) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL1029574 0.75 TSHR (0.60) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL10473930 0.74 TSHR (0.50) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL6751020 0.74
Pyridine SCHEMBL15309118 0.73 NAPRT (0.82) TSHRNAPRTTDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102952770-A Preparation method for cell catalyst with high regioselective acylation activity and microbiologic method for synthesizing cytosine arabinoside monoester UNIV SOUTH CHINA TECH 2013-03-06 CN claimed
CN-102952770-A Preparation method for cell catalyst with high regioselective acylation activity and microbiologic method for synthesizing cytosine arabinoside monoester UNIV SOUTH CHINA TECH 2013-03-06 CN disclosed
CN-101481720-A Method for enzyme-catalyzed synthesis of 5-aza cytidine ester derivative in mixed solvent UNIV SOUTH CHINA TECH (CN) 2009-07-15 CN disclosed
US-5101067-A Chemical intermediates for pyridinedicarboxylic acid esters, herbicides WACKER-CHEMIE GMBH (DE) 1992-03-31 US disclosed
US-5008392-A Reacting 2,3-dihalomaleic acid esters with ammonia or salts, reacting product with alpha, B-unsaturated aldehydes or ketones WACKER-CHEMIE GMBH (DE) 1991-04-16 US disclosed