Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971521 | 0.85 | ALDH1A1 (0.46) | MAPTSMN1; SMN2L3MBTL1CYP3A4ALDH1A1 | |
| SCHEMBL8579597 | 0.84 | L3MBTL1 (0.42) | MAPTSMN1; SMN2L3MBTL1ABCB1HSP90AB1 | |
| SCHEMBL28825380 | 0.84 | HSP90AB1 (0.36) | MAPTSMN1; SMN2L3MBTL1ABCB1HSP90AB1 | |
| SCHEMBL10871342 | 0.82 | L3MBTL1 (0.41) | MAPTSMN1; SMN2L3MBTL1ABCB1HSP90AB1 | |
| SCHEMBL97144 | 0.82 | KMT2A (0.46) | MAPTSMN1; SMN2L3MBTL1ABCB1HSP90AB1 | |
| SCHEMBL6342612 | 0.82 | CYP3A4 (0.40) | MAPTSMN1; SMN2CYP3A4ALDH1A1HPGD | |
| SCHEMBL5369405 | 0.81 | ERCC5 (0.39) | MAPTL3MBTL1CYP3A4ALDH1A1HPGD | |
| SCHEMBL10623096 | 0.81 | PTPN1 (0.50) | MAPTCYP3A4ALDH1A1HPGDTSHR | |
| SCHEMBL7515781 | 0.81 | ALDH1A1 (0.45) | MAPTSMN1; SMN2CYP3A4ALDH1A1HPGD | |
| SCHEMBL28713351 | 0.81 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026512-A2 | INHIBITORS OF MYC AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-105601627-B | Heteroaryl piperidine and heteroaryl based piperazine derivative as fungicide | 拜耳作物科学股份公司 | 2019-04-09 | — | — | CN | disclosed |
| CN-103180317-B | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-23 | — | — | CN | disclosed |
| CN-102781937-B | As two (difluoromethyl) pyrazoles of sterilant | BAYER CROPSCIENCE AG (DE) | 2015-09-30 | — | — | CN | disclosed |
| CN-103180317-A | Heteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH | 2013-06-26 | — | — | CN | disclosed |
| CN-102781937-A | Bis(difluormethyl)pyrazoles used as fungicides | BAYER CROPSCIENCE AG | 2012-11-14 | — | — | CN | disclosed |
| CN-1310707-C | Method for producing strongly adherent coatings | CIBA SC HOLDING AG (CH) | 2007-04-18 | — | — | CN | disclosed |
| CN-1622862-A | Method for producing strongly adherent coatings | CIBA SC HOLDING AG (CH) | 2005-06-01 | — | — | CN | disclosed |
| US-5103022-A | Reacting dl-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino -1-propanone with l-acetylphenylglycine to form corresponding diastereomeric salt, deposition, isolation of l-2-methyl-1-(4-trifluoromethylphenyl)-3-pyrrolidino-1-propanone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-04-07 | — | — | US | disclosed |
| US-5057535-A | Muscle relaxants | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0200942-A2 | New derivatives of an aminoketone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-11-12 | — | — | EP | disclosed |