Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 3/20 | 0.39 |
| ▸ | FEN1 | P39748 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678873 | 0.84 | ERCC5 (0.40) | ERCC5FEN1CYP3A4LMNANPC1 | |
| SCHEMBL9720642 | 0.81 | MAPT (0.40) | CYP3A4ALDH1A1HPGDKMT2AKDM4E | |
| SCHEMBL6342612 | 0.79 | CYP3A4 (0.40) | CYP3A4NPC1ALDH1A1CYP1A2HPGD | |
| SCHEMBL6355294 | 0.79 | TSHR (0.46) | CYP3A4LMNANPC1ALDH1A1CYP1A2 | |
| SCHEMBL29982561 | 0.79 | CYP3A4 (0.42) | CYP3A4LMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL24220 | 0.79 | CYP3A4 (0.42) | CYP3A4LMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL19971521 | 0.79 | ALDH1A1 (0.46) | CYP3A4LMNAALDH1A1CYP1A2HPGD | |
| SCHEMBL7515781 | 0.78 | ALDH1A1 (0.45) | CYP3A4LMNAALDH1A1CYP1A2HPGD | |
| SCHEMBL10623096 | 0.78 | PTPN1 (0.50) | CYP3A4LMNAALDH1A1CYP1A2HPGD | |
| SCHEMBL28713351 | 0.78 | CYP3A4 (0.39) | CYP3A4LMNAALDH1A1CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5202110-A | — | — | None | — | — | JP | disclosed |
| US-7279096-B2 | Polymer based permeable membrane for removal of ions | THE JOHNS HOPKINS UNIVERSITY (US) | 2007-10-09 | — | — | US | disclosed |
| US-7067702-B2 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY (US) | 2006-06-27 | — | — | US | disclosed |
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | THE JOHNS HOPKINS UNIVERSITY | 2006-03-30 | — | — | US | disclosed |
| US-20050019302-A1 | Polymer based permeable membrane for removal of ions | MURRAY GEORGE M (US) | 2005-01-27 | — | — | US | disclosed |
| US-6780323-B2 | Polymer based permeable membrane for removal of ions | THE JOHNS HOPKINS UNIVERSITY | 2004-08-24 | — | — | US | disclosed |
| US-20030113234-A1 | Polymer based permeable membrane for removal of ions | JOHNS HOPKINS UNIVERSITY, THE | 2003-06-19 | — | — | US | disclosed |
| WO-2003033575-A1 | POLYMER BASED PERMEABLE MEMBRANE FOR REMOVAL OF IONS | THE JOHNS HOPKINS UNIVERSITY (US) | 2003-04-24 | — | — | WO | disclosed |
| JP-H05202110-A | TRANSPARENT PLASTIC MATERIAL | SEIKO EPSON CORP | 1993-08-10 | — | — | JP | disclosed |
| EP-0549808-A1 | TRANSPARENT PLASTIC MATERIAL | SEIKO EPSON CORPORATION (JP) | 1993-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069288-A1 | Process for preparing vinyl substituted beta-diketones | VRK1, VRK2, DEK | ERCC5 3970/4885FEN1 2256/4885CYP3A4 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.