SCHEMBL9720668

SCHEMBL9720668

Cc1ccc(-c2nc(CN3CCCCC3)c(C)[nH]2)cc1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.55
DRD4 P21917 1/20 0.55
DRD3 P35462 1/20 0.55
CTSS P25774 12/20 0.53
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ACHE P22303 2/20 0.45
DHFR P00374 1/20 0.45
EGFR P00533 1/20 0.45
ERBB2 P04626 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
RCE1 Q9Y256 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
GRIN2B Q13224 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720664 0.93 DRD2 (0.62) DRD2DRD4DRD3CTSS
Hydrochloric Acid SCHEMBL10644520 0.86 DRD2 (0.56) DRD2DRD4DRD3CTSSGRIN2B
SCHEMBL8963868 0.84 DRD2 (0.63) DRD2DRD4DRD3CTSSSMN1; SMN2
SCHEMBL9725056 0.82 DRD4 (0.67) DRD2DRD4DRD3CTSSACHE
SCHEMBL8964084 0.82 DRD2 (0.52) DRD2DRD4DRD3CTSSSMN1; SMN2
SCHEMBL9720670 0.81 DRD4 (0.57) DRD2DRD4DRD3CTSSSMN1; SMN2
SCHEMBL9425835 0.81 DRD2 (0.54) DRD2DRD4DRD3CTSSSMN1; SMN2
SCHEMBL8963961 0.80 DRD2 (0.58) DRD2DRD4DRD3CTSS
Lifarizine SCHEMBL676318 0.79 DRD2 (0.57) DRD2DRD4DRD3CTSSSMN1; SMN2
SCHEMBL8963501 0.78 CTSS (0.52) DRD2DRD4DRD3CTSSSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142052-A Cationic effect-driven carbinol/amine reaction LABORATOIRES SYNTEX (FR) 1992-08-25 US disclosed