Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720695 | 1.00 | PSIP1 (0.56) | PSIP1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL17688632 | 0.89 | PSIP1 (0.50) | PSIP1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL17688692 | 0.89 | PSIP1 (0.50) | PSIP1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL17688630 | 0.89 | PSIP1 (0.50) | PSIP1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL10455034 | 0.84 | PSIP1 (0.74) | PSIP1GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL2264989 | 0.84 | PSIP1 (0.54) | PSIP1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL3696887 | 0.82 | TDP1 (0.57) | PSIP1GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL13790299 | 0.78 | THRB (0.51) | GAAMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9720835 | 0.78 | PSIP1 (0.43) | PSIP1GAAMAPTALDH1A1KMT2A | |
| SCHEMBL9720836 | 0.78 | PSIP1 (0.43) | PSIP1GAAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |