Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2642650 | 0.89 | PSIP1 (0.61) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL86088 | 0.89 | ALDH1A1 (0.67) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL23351954 | 0.89 | PSIP1 (0.61) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9908320 | 0.87 | PSIP1 (0.68) | PSIP1GAAALDH1A1CA2KMT2A | |
| Fluoresone SCHEMBL24999 | 0.87 | PSIP1 (0.58) | PSIP1GAAALDH1A1CA2KMT2A | |
| SCHEMBL1657371 | 0.87 | CA2 (0.59) | PSIP1GAACA2KMT2ALMNA | |
| SCHEMBL23043593 | 0.87 | PSIP1 (0.58) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL6496100 | 0.87 | PSIP1 (0.58) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL19622353 | 0.87 | PSIP1 (0.58) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1251768 | 0.87 | PSIP1 (0.58) | PSIP1GAAALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252009-B1 | 1,4-DISTYRYL BENZENE COMPOUNDS AND THEIR MIXTURES WITH OTHER 1,4-DISTYRYL BENZENE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-08-01 | — | — | EP | claimed |