SCHEMBL9720701

SCHEMBL9720701

CCCCN(CCCC)Cc1nc(-c2ccc(C)cc2)[nH]c1C

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 3/20 0.40
ATP4B P51164 3/20 0.40
SMPD3 Q9NY59 1/20 0.40
HRH3 Q9Y5N1 2/20 0.37
ACHE P22303 1/20 0.36
KCNH2 Q12809 2/20 0.36
MAPT P10636 1/20 0.36
TNKS O95271 2/20 0.35
PARP1 P09874 2/20 0.35
TNKS2 Q9H2K2 2/20 0.35
NISCH Q9Y2I1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720703 0.85 ACHE (0.41) SMPD3HRH3ACHEMAPTTNKS
SCHEMBL9720757 0.75 TNKS2 (0.38) ACHEMAPTTNKSPARP1TNKS2
SCHEMBL9720791 0.75 SMPD3 (0.40) SMPD3HRH3TNKSPARP1TNKS2
SCHEMBL9720663 0.73 HRH4 (0.44) SMPD3HRH3
SCHEMBL6649887 0.72 TNKS (0.41) SMPD3TNKSPARP1TNKS2NISCH
SCHEMBL19350091 0.72 CTSS (0.41) MAPTTNKSPARP1TNKS2NISCH
SCHEMBL9720698 0.71 GRIN2B (0.41) SMPD3MAPTTNKSPARP1TNKS2
Hydrochloric Acid SCHEMBL1437155 0.71 SMPD3 (0.40) SMPD3TNKSPARP1TNKS2
Hydrochloric Acid SCHEMBL8963760 0.71 CTSS (0.40) MAPTTNKSPARP1TNKS2NISCH
SCHEMBL9720691 0.71 NPSR1 (0.40) MAPTTNKSPARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142052-A Cationic effect-driven carbinol/amine reaction LABORATOIRES SYNTEX (FR) 1992-08-25 US disclosed