SCHEMBL9720716

SCHEMBL9720716

Oc1cccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)c1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.70
ATM Q13315 2/20 0.68
HDAC1 Q13547 2/20 0.64
CYP3A4 P08684 2/20 0.62
DRD2 P14416 2/20 0.62
DRD3 P35462 2/20 0.62
KCNH2 Q12809 2/20 0.62
USP2 O75604 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C19 P33261 1/20 0.62
HPN P05981 1/20 0.62
CHRM2 P08172 1/20 0.62
ADRA2A P08913 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
CHRM1 P11229 1/20 0.62
ADRA2C P18825 1/20 0.62
CNR1 P21554 1/20 0.62
DRD1 P21728 1/20 0.62
DRD4 P21917 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720786 0.85 ATM (0.59) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL7311276 0.85 ATM (0.84) OPRD1ATMHDAC1CYP3A4DRD2
Belarizine SCHEMBL2108057 0.84 ATM (0.73) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL9881223 0.83 OPRD1 (1.00) OPRD1ATMCYP3A4DRD2DRD3
Hydrochloric Acid SCHEMBL16226937 0.83 ATM (0.82) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL16226941 0.83 MEN1 (0.64) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL10827407 0.83 ATM (0.63) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL16226762 0.83 CYP3A4 (0.85) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL29599947 0.83 CYP3A4 (0.85) OPRD1ATMHDAC1CYP3A4DRD2
SCHEMBL2751728 0.82 OPRD1 (0.72) OPRD1ATMHDAC1CYP3A4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142052-A Cationic effect-driven carbinol/amine reaction LABORATOIRES SYNTEX (FR) 1992-08-25 US disclosed