Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720777 | 0.82 | ALDH1A1 (0.54) | HTR1AMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3395081 | 0.80 | ALDH1A1 (0.62) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8196250 | 0.80 | OPRM1 (0.62) | HTR1ATSHRUSP2MEN1KMT2A | |
| SCHEMBL12022723 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL12022746 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL12022757 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL12022722 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL15869610 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL12022716 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 | |
| SCHEMBL9991877 | 0.77 | HTR1A (0.58) | HTR1ALMNAALDH1A1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |