Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226160 | 0.88 | KDM4E (0.72) | KDM4EDRD4SIGMAR1IGF1RHTT | |
| SCHEMBL9720752 | 0.84 | DRD4 (0.77) | DRD4SIGMAR1ACHEBACE1 | |
| Belarizine SCHEMBL2108057 | 0.83 | ATM (0.73) | KDM4EDRD4L3MBTL1HTTATM | |
| SCHEMBL9720795 | 0.82 | CCR2 (0.54) | DRD4L3MBTL1SIGMAR1 | |
| SCHEMBL5428090 | 0.80 | DRD4 (0.63) | KDM4EDRD4SIGMAR1ACHEBACE1 | |
| SCHEMBL10362355 | 0.77 | KDM4E (0.74) | KDM4ESIGMAR1IGF1RHTTATM | |
| SCHEMBL10515610 | 0.77 | BACE1 (0.57) | DRD4L3MBTL1SIGMAR1ACHEBACE1 | |
| SCHEMBL9720751 | 0.77 | KCNH2 (0.71) | KDM4EDRD4SIGMAR1HTTATM | |
| SCHEMBL4468044 | 0.77 | KDM4E (1.00) | KDM4ESIGMAR1IGF1RHTTATM | |
| SCHEMBL4465545 | 0.77 | KDM4E (1.00) | KDM4ESIGMAR1IGF1RHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |