SCHEMBL9720799

SCHEMBL9720799

CC(C)C1=CC=CC(c2ccccc2O)(c2ccccc2O)C1C(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675499 0.76
SCHEMBL25419134 0.66
SCHEMBL647589 0.65 MEN1 (0.34)
SCHEMBL5244034 0.57 HSD11B1 (0.41) GABRA1GABRB2
SCHEMBL3132046 0.55 ALOX5AP (0.40)
SCHEMBL9818107 0.54 MAPK1 (0.39)
SCHEMBL382439 0.54 ESR1 (0.50)
SCHEMBL29482233 0.54 ESR1 (0.50)
SCHEMBL28382869 0.54 ALDH1A1 (0.43) GABRA1GABRB2
SCHEMBL29646285 0.54 ESR1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-5162461-A Thermoplastic polyblends of aromatic polycarbonates and thermoplastic polyurethanes THE DOW CHEMICAL COMPANY (US) 1992-11-10 US disclosed