Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720913 | 0.81 | NPSR1 (0.55) | UBE2NTDP1KDM4EALDH1A1GAA | |
| SCHEMBL9721010 | 0.77 | CMA1 (0.52) | UBE2NTDP1KDM4EALDH1A1GAA | |
| SCHEMBL9720892 | 0.75 | UBE2N (0.52) | UBE2NTDP1KDM4EALDH1A1LMNA | |
| SCHEMBL9290314 | 0.75 | ALDH1A1 (0.44) | UBE2NTDP1KDM4EALDH1A1GAA | |
| SCHEMBL9720959 | 0.74 | LMNA (0.51) | UBE2NTDP1KDM4EALDH1A1GAA | |
| SCHEMBL9720885 | 0.74 | KDM4E (0.61) | UBE2NTDP1KDM4EALDH1A1GAA | |
| SCHEMBL4597340 | 0.71 | CHRM5 (0.73) | TDP1ALDH1A1ATMCA9HPGD | |
| SCHEMBL18669003 | 0.71 | CA9 (0.61) | KDM4EALDH1A1GAALMNAATM | |
| SCHEMBL9720888 | 0.70 | ALDH1A1 (0.47) | UBE2NKDM4EALDH1A1GAALMNA | |
| SCHEMBL18974314 | 0.69 | CHRM5 (0.55) | KDM4EALDH1A1GAALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |