Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | UBE2N | P61088 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CLTC | Q00610 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720892 | 0.87 | UBE2N (0.52) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL9720913 | 0.86 | NPSR1 (0.55) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL9720994 | 0.82 | UBE2N (0.74) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL9721010 | 0.77 | CMA1 (0.52) | UBE2NHPGDL3MBTL1ATMALDH1A1 | |
| SCHEMBL9720885 | 0.76 | KDM4E (0.61) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL9720888 | 0.74 | ALDH1A1 (0.47) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL9720883 | 0.74 | UBE2N (0.50) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL11373888 | 0.72 | HEXA (0.57) | LMNAHPGDL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9721061 | 0.71 | NPSR1 (0.49) | LMNAUBE2NHPGDL3MBTL1ATM | |
| SCHEMBL9290314 | 0.71 | ALDH1A1 (0.44) | LMNAUBE2NHPGDL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |