Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374786 | 0.92 | ALDH1A1 (0.44) | POLBMEN1MAPK1KMT2ACYP1A2 | |
| SCHEMBL11373888 | 0.85 | HEXA (0.57) | POLBMEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9720969 | 0.83 | ALDH1A1 (0.66) | POLBMEN1MAPK1KMT2ACYP1A2 | |
| SCHEMBL11369587 | 0.80 | POLB (0.59) | POLBMEN1MAPK1KMT2ACYP1A2 | |
| SCHEMBL9720888 | 0.80 | ALDH1A1 (0.47) | POLBMEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL9720814 | 0.78 | CDC25A (0.48) | MEN1MAPK1KMT2AALDH1A1HPGD | |
| SCHEMBL11377100 | 0.75 | ALDH1A1 (0.62) | POLBMEN1MAPK1KMT2ACYP1A2 | |
| SCHEMBL11369583 | 0.75 | POLB (0.44) | POLBMEN1MAPK1KMT2ACYP1A2 | |
| SCHEMBL11369586 | 0.75 | POLB (0.44) | POLBMEN1MAPK1KMT2ACYP1A2 | |
| SCHEMBL6263721 | 0.75 | POLB (0.76) | POLBMEN1MAPK1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |
| US-4261896-A | INDIBITORS OF PLATELET AGGREGATION | AMERICAN CYANAMID COMPANY (US) | 1981-04-14 | — | — | US | disclosed |