Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183774 | 0.85 | TSHR (0.46) | TSHRCYP3A4S1PR2 | |
| SCHEMBL10652897 | 0.83 | TSHR (0.33) | TSHRCYP3A4S1PR2 | |
| SCHEMBL11368669 | 0.83 | CDK2 (0.38) | TSHRCYP3A4 | |
| SCHEMBL11322704 | 0.78 | KDM4E (0.34) | TSHRCYP3A4S1PR2PDE10A | |
| SCHEMBL11258560 | 0.78 | S1PR2 (0.33) | TSHRCYP3A4S1PR2PDE10A | |
| SCHEMBL10379189 | 0.78 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL2608422 | 0.74 | GABRA1 (0.42) | TSHRS1PR2PDE10A | |
| SCHEMBL561772 | 0.74 | ALDH1A1 (0.40) | TSHRCYP3A4 | |
| SCHEMBL11179412 | 0.73 | NPC1 (0.34) | S1PR2 | |
| SCHEMBL1538847 | 0.73 | TSHR (0.47) | TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402536-A1 | Preparation of 2,3,4,6-tetrachloropyridine | THE DOW CHEMICAL COMPANY (US) | 1990-12-19 | — | — | EP | claimed |
| US-4849523-A | CHLORINATION OF 2,3,6-TRICHLORO-4-/TRICHLOROR-METHYL/ PYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1989-07-18 | — | — | US | claimed |
| JP-3031262-A | — | — | None | — | — | JP | disclosed |
| US-5166352-A | Pyridinecarboxylic acid chlorides from (trichloromethyl)pyridines | DOWELANCO (US) | 1992-11-24 | — | — | US | disclosed |
| JP-H0331262-A | PROCESS FOR PREPARING 2,3,4,6-TETRACHLOROPYRIDINE | DOW CHEM CO:THE | 1991-02-12 | — | — | JP | disclosed |
| EP-0402536-A1 | Preparation of 2,3,4,6-tetrachloropyridine | THE DOW CHEMICAL COMPANY (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0110690-B1 | PREPARATION OF (TRIFLUOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4849523-A | CHLORINATION OF 2,3,6-TRICHLORO-4-/TRICHLOROR-METHYL/ PYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4849523-A | CHLORINATION OF 2,3,6-TRICHLORO-4-/TRICHLOROR-METHYL/ PYRIDINE | THE DOW CHEMICAL COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| US-4745193-A | Process for the preparation of fluoromethylpyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-17 | — | — | US | disclosed |
| US-4590279-A | CATALYTIC FLUORINATION OF (TRICHLOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0004434-B1 | HALOMETHYL SUBSTITUTED DIALKOXYPYRIDINES, FUNGICIDAL COMPOSITION, AND METHOD FOR PROTECTING PLANTS FROM FUNGAL DISEASE | THE DOW CHEMICAL COMPANY (US) | 1981-09-30 | — | — | EP | disclosed |
| EP-0004435-B1 | ETHERS OF 4-HALOMETHYLPYRIDINES, FUNGICIDAL COMPOSITIONS AND METHOD FOR PROTECTING PLANTS FROM FUNGAL DISEASE | THE DOW CHEMICAL COMPANY (US) | 1981-07-01 | — | — | EP | disclosed |
| US-4266964-A | SAID ANTIDOTES BEING CHLOROPYRIDINE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| US-4190662-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| EP-0004434-A2 | Halomethyl substituted dialkoxypyridines, fungicidal composition, and method for protecting plants from fungal disease | THE DOW CHEMICAL COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
| EP-0004435-A2 | Ethers of 4-halomethylpyridines, fungicidal compositions and method for protecting plants from fungal disease | THE DOW CHEMICAL COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
| US-4143144-A | PLANT FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4108859-A | FUNGICIDES FOR PAINTS | THE DOW CHEMICAL COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4062962-A | Substituted pyridines as systemic plant protectants | THE DOW CHEMICAL COMPANY (US) | 1977-12-13 | — | — | US | disclosed |