Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.38 |
| ▸ | RELA | Q04206 | 4/20 | 0.38 |
| ▸ | JUN | P05412 | 3/20 | 0.38 |
| ▸ | XPO1 | O14980 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28186521 | 0.87 | CES2 (0.39) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL4703323 | 0.85 | ADORA2A (0.39) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL12788231 | 0.85 | TACR1 (0.37) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL11109288 | 0.84 | S1PR1 (0.36) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL29560454 | 0.84 | NOS3 (0.45) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL23181498 | 0.84 | GABRB3 (0.36) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL562878 | 0.84 | HSP90AA1 (0.39) | GABRA2GABRB2GABRB3NPC1RAB9A | |
| SCHEMBL29256257 | 0.84 | XPO1 (0.36) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL29659055 | 0.84 | HSP90AA1 (0.39) | GABRA2GABRB2GABRB3NPC1RAB9A | |
| SCHEMBL2087532 | 0.84 | NOS3 (0.45) | ALDH1A1CYP3A4HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790168-B | Preparation method of 2-amino-4-trifluoromethyl pyridine and 2-amino-4-trifluoromethyl pyridine | 上海素馨化工科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-111151248-A | Method for catalyzing heterocyclic halogen-containing organic matter hydrogenation dehalogenation by using supported metal oxide | 浙江大学 | 2020-05-15 | — | — | CN | claimed |
| US-4563529-A | VAPOR PHASE CATALYTIC FLUORINATION OF PICOLINES OR LUTIDINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1986-01-07 | — | — | US | claimed |
| EP-0042696-B1 | PROCESS FOR PRODUCING TRIFLUOROMETHYLPYRIDINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-11-16 | — | — | EP | claimed |
| EP-0042696-A1 | Process for producing trifluoromethylpyridines | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-12-30 | — | — | EP | claimed |
| JP-4005273-A | — | — | None | — | — | JP | disclosed |
| US-12630528-B2 | Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof | LG CHEM, LTD. (KR) | 2026-05-19 | — | — | US | disclosed |
| US-12630534-B2 | 1-((1H-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds as GPR139 antagonists for the treatment of e.g. depression | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12590086-B2 | 3-((1H-pyrazol-4-yl)methyl)-6′-(phenyl)-2H-(1,2′-bipyridin)-2-one derivatives and related compounds as GPR139 antagonists for use in a method of treatment of e.g. depression | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-03-31 | — | — | US | disclosed |
| EP-4695259-A1 | TRICYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| US-20260035367-A1 | PKC-Theta Modulators | CELGENE CORPORATION (US) | 2026-02-05 | — | — | US | disclosed |
| US-20260022130-A1 | HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2026-01-22 | — | — | US | disclosed |
| US-4649201-A | SOLVENT EXTRACTION, ALKYLENE GLYCOL | THE DOW CHEMICAL COMPANY (US) | 1987-03-10 | — | — | US | disclosed |
| US-4563529-A | VAPOR PHASE CATALYTIC FLUORINATION OF PICOLINES OR LUTIDINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0042696-B1 | PROCESS FOR PRODUCING TRIFLUOROMETHYLPYRIDINES | ISHIHARA SANGYO KAISHA LTD. (JP) | 1983-11-16 | — | — | EP | disclosed |
| EP-0042696-A1 | Process for producing trifluoromethylpyridines | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-12-30 | — | — | EP | disclosed |
| EP-0004434-B1 | HALOMETHYL SUBSTITUTED DIALKOXYPYRIDINES, FUNGICIDAL COMPOSITION, AND METHOD FOR PROTECTING PLANTS FROM FUNGAL DISEASE | THE DOW CHEMICAL COMPANY (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4203988-A | ANTISECRETORY AGENTS | MERCK & CO., INC. (US) | 1980-05-20 | — | — | US | disclosed |
| US-4190662-A | FUNGICIDES | THE DOW CHEMICAL COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| EP-0004434-A2 | Halomethyl substituted dialkoxypyridines, fungicidal composition, and method for protecting plants from fungal disease | THE DOW CHEMICAL COMPANY (US) | 1979-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022130-A1 | HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS | LIPC, LIPA, LPL | ALDH1A1 1338/4885CYP3A4 784/4885HPGD 2377/4885 |
| US-20260035367-A1 | PKC-Theta Modulators | PRKAR2B, PRKAR2A, PRKCD | ALDH1A1 4459/4885CYP3A4 2376/4885HPGD 3114/4885 |
| US-12590086-B2 | 3-((1H-pyrazol-4-yl)methyl)-6′-(phenyl)-2H-(1,2′-bipyridin)-2-one derivatives and related compounds as GPR139 antagonists for use in a method of treatment of e.g. depression | GPR139, OPRL1, GRIN2C | ALDH1A1 1460/4885CYP3A4 1767/4885HPGD 3996/4885 |
| US-12630528-B2 | Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof | DGAT2, DGAT1, SOAT2 | ALDH1A1 597/4885CYP3A4 1556/4885HPGD 2277/4885 |
| US-12630534-B2 | 1-((1H-pyrazol-4-yl)methyl)-3-(phenyl)-1,3-dihydro-2H-imidazol-2-one derivatives and related compounds as GPR139 antagonists for the treatment of e.g. depression | GPR139, OPRL1, GRIN2C | ALDH1A1 1685/4885CYP3A4 2449/4885HPGD 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.