Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | MPI | P34949 | 1/20 | 0.63 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.63 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CLTC | Q00610 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11373746 | 0.87 | UBE2N (0.76) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL9720966 | 0.86 | NPSR1 (0.79) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL30517067 | 0.85 | KDM4E (0.82) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL22532960 | 0.85 | KDM4E (0.82) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL9720959 | 0.82 | LMNA (0.51) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL8737445 | 0.79 | CASP3 (0.65) | HPGDNPSR1CA12CA1CA2 | |
| SCHEMBL29820192 | 0.79 | CASP3 (0.65) | HPGDNPSR1CA12CA1CA2 | |
| SCHEMBL6270684 | 0.78 | ALDH1A1 (1.00) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL29437299 | 0.78 | ALDH1A1 (1.00) | UBE2NHPGDL3MBTL1LMNAATM | |
| SCHEMBL14557200 | 0.78 | CLTC (0.64) | UBE2NHPGDL3MBTL1LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079247-A | N1 -substituted benz(cd)indol-2-imine compounds as cardiovascular agents | AMERICAN CYANAMID COMPANY (US) | 1992-01-07 | — | — | US | disclosed |