⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807930 | 0.75 | — | — | |
| SCHEMBL2869141 | 0.70 | CA12 (0.39) | — | |
| SCHEMBL13285686 | 0.70 | — | — | |
| SCHEMBL11755220 | 0.69 | — | — | |
| SCHEMBL16781758 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL25796244 | 0.65 | PRKCA (0.33) | — | |
| Cyclohexane SCHEMBL9279245 | 0.65 | CA12 (0.35) | — | |
| SCHEMBL18596895 | 0.65 | — | — | |
| SCHEMBL2797756 | 0.65 | HCAR2 (0.31) | — | |
| SCHEMBL6177814 | 0.64 | CTSK (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812033-B | Novel synthesis method of oseltamivir | 山东大学 | 2022-02-15 | — | — | CN | disclosed |
| CN-112812033-A | Novel synthesis method of oseltamivir | 山东大学 | 2021-05-18 | — | — | CN | disclosed |
| US-10385010-B1 | Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| EP-2190439-B1 | OSELTAMIVIR PHOSPHONATE DERIVATIVES WITH ANTI-INFLUENZA ACTIVITY AND SYNTHESIS THEREOF | ACADEMIA SINICA (TW) | 2016-03-09 | — | — | EP | disclosed |
| US-8304553-B2 | Method of forming oseltamivir and derivatives thereof | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-11-06 | — | — | US | disclosed |
| US-7888337-B2 | Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity | ACADEMIA SINICA (TW) | 2011-02-15 | — | — | US | disclosed |
| US-20110021762-A1 | METHOD OF FORMING OSELTAMIVIR AND DERIVATIVES THEREOF | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2011-01-27 | — | — | US | disclosed |
| EP-2190439-A2 | SYNTHESIS OF OSELTAMIVIR CONTAINING PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY | Academia Sinica (TW) | 2010-06-02 | — | — | EP | disclosed |
| US-20100113397-A1 | SYNTHESIS OF OSELTAMIVIR CONTAINING PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY | ACADEMIA SINICA (TW) | 2010-05-06 | — | — | US | disclosed |
| WO-2009078813-A1 | METHOD OF FORMING OSELTAMIVIR AND DERIVATIVES THEREOF | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009029888-A2 | SYNTHESIS OF OSELTAMIVIR CONTAINING PHOSPHONATE CONGENERS WITH ANTI-INFLUENZA ACTIVITY | WONG CHI-HUEY (US) | 2009-03-05 | — | — | WO | disclosed |