Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721954 | 0.78 | ALDH1A1 (0.51) | MAPTKDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL9722085 | 0.77 | MAPT (0.53) | MAPTKDM4ERAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30015078 | 0.75 | NPC1 (0.68) | KDM4EPOLBALDH1A1L3MBTL1SENP8 | |
| SCHEMBL2305236 | 0.75 | NPC1 (0.68) | KDM4EPOLBALDH1A1L3MBTL1SENP8 | |
| SCHEMBL14776981 | 0.73 | KDM4E (0.48) | MAPTKDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL8119165 | 0.73 | NPC1 (0.60) | MAPTKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL9447108 | 0.71 | NPC1 (0.54) | MAPTKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL1206979 | 0.70 | EIF4E (0.65) | SENP8SENP7SENP6RAB9ANPC1 | |
| SCHEMBL19509922 | 0.70 | RAB9A (0.56) | MAPTKDM4EALDH1A1L3MBTL1RAB9A | |
| SCHEMBL1715816 | 0.70 | RAB9A (0.56) | MAPTKDM4EALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103014-A | Antiinflammatory or/and antiallergic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |
| US-4942236-A | ANTIASTHMATICS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-07-17 | — | — | US | disclosed |
| US-4895953-A | 2-Aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4826990-A | LIPOXYGENASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0310370-A1 | 2-aryl substituted heterocyclic compounds as antiallgeric and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-04-05 | — | — | EP | disclosed |