Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.61 |
| ▸ | HTR2A | P28223 | 10/20 | 0.61 |
| ▸ | HTR1A | P08908 | 10/20 | 0.61 |
| ▸ | DRD3 | P35462 | 5/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182895 | 0.93 | HTR1A (0.56) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9188284 | 0.92 | HTR1A (0.57) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722367 | 0.88 | DRD2 (0.52) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL9722283 | 0.87 | KDM4E (0.51) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722267 | 0.85 | DRD2 (0.49) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722222 | 0.84 | HTR1A (0.53) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722279 | 0.80 | DRD2 (0.58) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722272 | 0.80 | DRD2 (0.58) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL7276066 | 0.79 | HTR1A (0.66) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL30579539 | 0.79 | HTR1A (0.80) | DRD2HTR2AHTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |