Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9722283 | 0.99 | KDM4E (0.51) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722267 | 0.97 | DRD2 (0.49) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722272 | 0.88 | DRD2 (0.58) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722279 | 0.88 | DRD2 (0.58) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722174 | 0.88 | DRD2 (0.61) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9182895 | 0.86 | HTR1A (0.56) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9188284 | 0.85 | HTR1A (0.57) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722202 | 0.85 | DRD2 (0.59) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL9722226 | 0.83 | DRD2 (0.46) | DRD2HTR2AHTR1ADRD3KCNH2 | |
| SCHEMBL10845187 | 0.80 | DRD2 (0.68) | DRD2HTR2AHTR1ADRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |