Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9467374 | 0.96 | KDM4E (0.43) | MTNR1AMTNR1BKDM4EUSP2ALDH1A1 | |
| SCHEMBL4637265 | 0.82 | MTNR1A (0.42) | MTNR1AMTNR1BKDM4EUSP2ALDH1A1 | |
| SCHEMBL9370324 | 0.81 | MTNR1A (0.39) | MTNR1AMTNR1BSLC9A3HTR2A | |
| SCHEMBL11845112 | 0.79 | HTR2A (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL7279155 | 0.73 | CA2 (0.44) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL5635575 | 0.73 | IDO1 (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL11845812 | 0.73 | HTR2A (0.38) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL10732206 | 0.73 | HTR2A (0.41) | MTNR1AMTNR1BKDM4EUSP2ALDH1A1 | |
| SCHEMBL11837153 | 0.73 | HTR2A (0.46) | HTR2A | |
| SCHEMBL14143008 | 0.70 | CA2 (0.45) | MTNR1AMTNR1BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |