Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.60 |
| ▸ | DRD2 | P14416 | 8/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722234 | 1.00 | HTR2A (0.60) | HTR2ADRD2HTR1AHTR7HTR2C | |
| SCHEMBL9187663 | 0.90 | HTR2A (0.53) | HTR2ADRD2HTR1AHTR7HTR2C | |
| Hydrochloric Acid SCHEMBL9722317 | 0.89 | HTR2A (0.52) | HTR2ADRD2HTR1AHTR7HTR2C | |
| SCHEMBL9722271 | 0.87 | HTR2A (0.58) | HTR2ADRD2HTR1A | |
| SCHEMBL9722277 | 0.87 | HTR2A (0.58) | HTR2ADRD2HTR1A | |
| SCHEMBL9383070 | 0.84 | DRD2 (0.62) | HTR2ADRD2HTR2CACHE | |
| SCHEMBL9378097 | 0.84 | DRD2 (0.62) | HTR2ADRD2HTR2CACHE | |
| SCHEMBL9722264 | 0.78 | DRD2 (0.50) | HTR2ADRD2HTR1AHTR7KCNH2 | |
| SCHEMBL9722260 | 0.78 | DRD2 (0.50) | HTR2ADRD2HTR1AHTR7KCNH2 | |
| Fumaric Acid SCHEMBL9682262 | 0.77 | DRD2 (0.57) | HTR2ADRD2HTR2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |