Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | HTR2A | P28223 | 6/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722260 | 1.00 | DRD2 (0.50) | DRD2HTR2AHTR1APIN1HTR7 | |
| SCHEMBL9379037 | 0.85 | DRD2 (0.51) | DRD2HTR2A | |
| SCHEMBL9722237 | 0.78 | HTR2A (0.60) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL9722234 | 0.78 | HTR2A (0.60) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL9722220 | 0.77 | DRD2 (0.43) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL9681618 | 0.73 | HTR2A (0.48) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| SCHEMBL9187663 | 0.72 | HTR2A (0.53) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| Hydrochloric Acid SCHEMBL9722317 | 0.71 | HTR2A (0.52) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| Fumaric Acid SCHEMBL7772698 | 0.70 | HTR2A (0.47) | DRD2HTR2AHTR1AHTR7KCNH2 | |
| Fumaric Acid SCHEMBL7772700 | 0.70 | HTR2A (0.47) | DRD2HTR2AHTR1AHTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |