Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 0.51 |
| ▸ | HTR2A | P28223 | 17/20 | 0.51 |
| ▸ | DRD2 | P14416 | 13/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722278 | 1.00 | HTR1A (0.51) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL9722226 | 0.90 | DRD2 (0.46) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL9184054 | 0.84 | HTR2A (0.52) | HTR1AHTR2ADRD2DRD3 | |
| SCHEMBL9722272 | 0.84 | DRD2 (0.58) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL9722279 | 0.84 | DRD2 (0.58) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL9722222 | 0.83 | HTR1A (0.53) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL9722367 | 0.75 | DRD2 (0.52) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| Hydrochloric Acid SCHEMBL9722283 | 0.74 | KDM4E (0.51) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL10845187 | 0.74 | DRD2 (0.68) | HTR1AHTR2ADRD2KCNH2DRD3 | |
| SCHEMBL9722267 | 0.72 | DRD2 (0.49) | HTR1AHTR2ADRD2KCNH2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173490-A | Antipsychotic drugs having no side effects; anxiolytic agents; analgesics; tranquilizers; sedatives; antidepressants | ADIR ET COMPAGNIE (FR) | 1992-12-22 | — | — | US | disclosed |