Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760417 | 0.70 | CNR1 (0.50) | CNR1CNR2TRPA1 | |
| SCHEMBL30027246 | 0.70 | CNR1 (0.50) | CNR1CNR2TRPA1 | |
| SCHEMBL69199 | 0.66 | HPGD (0.41) | CNR1CNR2ALOX15 | |
| SCHEMBL9722386 | 0.65 | HMGCR (0.41) | CYP1A2CNR1CNR2TRPA1TRPV1 | |
| SCHEMBL6573311 | 0.64 | CNR1 (0.41) | CNR1CNR2ESR1ESR2ALOX15 | |
| SCHEMBL15255041 | 0.63 | CNR1 (0.43) | CNR1CNR2ESR1 | |
| SCHEMBL7597643 | 0.62 | TP53 (0.37) | TP53CYP1A2CNR1CNR2 | |
| SCHEMBL23387417 | 0.61 | NOS2 (0.42) | CYP1A2CNR1CNR2ESR1ESR2 | |
| SCHEMBL6235059 | 0.61 | CNR1 (0.42) | TP53CYP1A2CNR1CNR2 | |
| SCHEMBL981537 | 0.61 | PRKCI (0.48) | TP53CNR1CNR2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149834-A | Anticholesterol agent and enzyme inhibitors, for curing arteriosclerosis | FUJIREBIO INC. (JP) | 1992-09-22 | — | — | US | disclosed |