SCHEMBL6235059

SCHEMBL6235059

CCCc1c(O)ccc(O)c1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
HPGD P15428 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
PRKCI P41743 1/20 0.36
POLB P06746 1/20 0.34
FYN P06241 1/20 0.33
ALOX5 P09917 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
HIF1A Q16665 2/20 0.33
GLA P06280 1/20 0.33
MCL1 Q07820 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28871536 0.87 CNR1 (0.39) CNR1CNR2HPGDKDM4EALDH1A1
SCHEMBL1760417 0.83 CNR1 (0.50) CNR1CNR2HPGDKDM4EALDH1A1
SCHEMBL30027246 0.83 CNR1 (0.50) CNR1CNR2HPGDKDM4EALDH1A1
SCHEMBL10908327 0.83 ALDH1A1 (0.38) CNR1CNR2HPGDKDM4EALDH1A1
SCHEMBL28797265 0.80 CNR1 (0.41) CNR1CNR2HPGDKDM4EALDH1A1
SCHEMBL18371594 0.79 HPGD (0.39) CNR1CNR2HPGDKDM4EALDH1A1
SCHEMBL11079390 0.76 PRKCI (0.47) CNR1CNR2PRKCIALOX5HTT
SCHEMBL9560533 0.75 ALOX5 (0.41) CNR1CNR2ALOX5MCL1
SCHEMBL28871530 0.75 NPC1 (0.46) HPGDKDM4EALDH1A1GAANPC1
SCHEMBL1798100 0.75 CNR1 (0.37) CNR1CNR2HPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1215103-C Process for the preparation of polycarbonates DOW GLOBAL TECHNOLOGIES CO (US) 2005-08-17 CN disclosed
EP-1274762-B1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2005-05-11 EP disclosed
CN-1420901-A Polycarbonate preparation process DOW GLOBAL TECHNOLOGIES CO (US) 2003-05-28 CN disclosed
US-6225436-B1 REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION THE DOW CHEMICAL COMPANY 2001-05-01 US disclosed
EP-0699702-A2 Reaction products of carbonyl compounds and dihydric phenols THE DOW CHEMICAL COMPANY (US) 1996-03-06 EP disclosed
US-4680370-A Branched polycarbonate composition from tris(hydroxyaryl)phosphorus compound THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed
US-4595733-A Aromatic polycarbonate containing thieno-2-one-5,5-dioxide terminal groups GENERAL ELECTRIC COMPANY (US) 1986-06-17 US disclosed
EP-0177792-A1 Hydrolytically stabilized polycarbonates GENERAL ELECTRIC COMPANY (US) 1986-04-16 EP disclosed
EP-0176008-A1 Aromatic polymers containing novel terminal groups GENERAL ELECTRIC COMPANY (US) 1986-04-02 EP disclosed
US-4576982-A Hydrolytically stabilized polycarbonates GENERAL MOTORS COMPANY (US) 1986-03-18 US disclosed
US-4168368-A STRESS RESISTANCE THE DOW CHEMICAL COMPANY (US) 1979-09-18 US disclosed
US-4156769-A Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1979-05-29 US disclosed
US-4111910-A POLYCARBONATES HAVING CARBAMATE TERMINAL GROUPS THE DOW CHEMICAL COMPANY (US) 1978-09-05 US disclosed
US-4100139-A Polycarbonates incorporating epihalohydrin residues THE DOW CHEMICAL COMPANY (US) 1978-07-11 US disclosed
US-4059566-A Process for controlling the molecular weight of polycarbonates using ammonia or ammonia compounds THE DOW CHEMICAL COMPANY (US) 1977-11-22 US disclosed
US-4055544-A Process for making polycarbonates using ammonia or ammonia compounds as the catalysts THE DOW CHEMICAL COMPANY (US) 1977-10-25 US disclosed
US-4020045-A METALLIC SULFITES THE DOW CHEMICAL COMPANY (US) 1977-04-26 US disclosed
US-3992357-A THERMOPLASTIC THE DOW CHEMICAL COMPANY (US) 1976-11-16 US disclosed