Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722782 | 0.81 | CISD2 (0.35) | ALOX15ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9722702 | 0.80 | ALOX15 (0.46) | ALOX15ALDH1A1HSD17B10MAPTTAAR1 | |
| SCHEMBL9722770 | 0.69 | ALDH1A1 (0.33) | ALOX15ALDH1A1HPGDTSHRRECQL | |
| SCHEMBL9722804 | 0.68 | ALOX15 (0.57) | ALOX15HPGDTSHRTAAR1TP53 | |
| SCHEMBL9722791 | 0.64 | TAAR1 (0.44) | ALOX15ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9648315 | 0.62 | ALDH1A1 (0.42) | ALOX15ALDH1A1HPGDTSHRRECQL | |
| SCHEMBL23330896 | 0.61 | GSK3B (0.65) | ALOX15ALDH1A1HPGDTSHRRECQL | |
| SCHEMBL10703134 | 0.61 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10TDP1GAA | |
| SCHEMBL12608267 | 0.60 | MEN1 (0.52) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL17238833 | 0.59 | KDM4E (0.38) | ALDH1A1HPGDGAAKDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |