Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722711 | 0.76 | CRHBP (0.61) | CRHBPCRHR2GAAHTTSMN1; SMN2 | |
| SCHEMBL11861407 | 0.72 | GAA (1.00) | CRHBPCRHR2GAAHTTSMN1; SMN2 | |
| SCHEMBL5061103 | 0.71 | CCR1 (0.60) | CRHBPCRHR2GAAHTTTSHR | |
| SCHEMBL64347 | 0.71 | TDP1 (0.74) | CRHBPCRHR2TSHRMAPTMEN1 | |
| SCHEMBL9722688 | 0.71 | TDP1 (0.54) | CRHBPCRHR2HTTTSHRSMN1; SMN2 | |
| SCHEMBL16738475 | 0.71 | GPBAR1 (0.65) | CRHBPCRHR2 | |
| SCHEMBL655032 | 0.68 | HTT (0.78) | GAAHTTTSHRSMN1; SMN2HPGD | |
| SCHEMBL18716598 | 0.68 | GAA (0.58) | CRHBPCRHR2GAATSHRSMN1; SMN2 | |
| SCHEMBL9722699 | 0.68 | CRHBP (0.51) | CRHBPCRHR2GAAHTTTSHR | |
| SCHEMBL11812771 | 0.66 | MEN1 (0.52) | CRHBPCRHR2HTTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139564-A | Applying postemergence | PARK SANG W (KR) | 1992-08-18 | — | — | US | disclosed |