Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386999 | 0.80 | ALDH1A1 (0.33) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL276579 | 0.74 | BCL2L1 (0.39) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL1941287 | 0.70 | ALDH1A1 (0.40) | ALDH1A1ALOX15HSD17B10MAPTHPGD | |
| SCHEMBL5031420 | 0.67 | ALDH1A1 (0.35) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL1042592 | 0.65 | MAPT (0.63) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL5918581 | 0.65 | ALOX15 (0.60) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL15899337 | 0.62 | CD44 (0.32) | ALDH1A1TSHRCA2CA1 | |
| SCHEMBL624344 | 0.62 | CYP3A4 (0.32) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL6749423 | 0.62 | BCL2L1 (0.41) | ALDH1A1ALOX15HSD17B10TDP1MAPT | |
| SCHEMBL21048130 | 0.62 | MAPT (0.53) | ALDH1A1ALOX15HSD17B10TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885357-B1 | INKS FOR INK-JET PRINTING | FUJIFILM IMAGING COLORANTS INC (US) | 2018-06-13 | — | — | EP | claimed |
| US-9540532-B2 | Inks for ink-jet printing | FUJIFILM IMAGING COLORANTS, INC. (US) | 2017-01-10 | — | — | US | claimed |
| US-20150184013-A1 | Inks for Ink-Jet Printing | FUJIFILM IMAGING COLORANTS, INC. | 2015-07-02 | — | — | US | claimed |
| US-20120306962-A1 | INKS | FUJIFILM IMAGING COLORANTS, INC. | 2012-12-06 | — | — | US | claimed |
| US-7056376-B2 | Printing process using specified AZO compounds | AVECIA LIMITED (GB) | 2006-06-06 | — | — | US | claimed |
| EP-1516021-B1 | PRINTING PROCESS USING SPECIFIED AZO COMPOUNDS | FUJIFILM IMAGING COLORANTS LTD (GB) | 2006-05-17 | — | — | EP | claimed |
| US-20040020404-A1 | Printing process using specified AZO compounds | AVECIA LIMITED | 2004-02-05 | — | — | US | claimed |
| US-20010041794-A1 | Nucleotide analogs | GILEAD SCIENCES, INC. | 2001-11-15 | — | — | US | claimed |
| US-5798340-A | ANTITUMOR/ANTINEOPLASTIC ACTIITY, VIRICIDES; BROAD SPECTRUM MICROBIOCIDES; THIOPHOSPHONATES HYDROLYZABLE IN VIVO; ORAL ADMINISTRATION; BIOAVAILABILITY; NONTOXIC; POTENCY | GILEAD SCIENCES, INC. (US) | 1998-08-25 | — | — | US | claimed |
| US-20190345190-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2019-11-14 | — | — | US | disclosed |
| US-20190315785-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2019-10-17 | — | — | US | disclosed |
| EP-2885357-B1 | INKS FOR INK-JET PRINTING | FUJIFILM IMAGING COLORANTS INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9957225-B2 | Treatment of friedreich's ataxia using histone deacetylase inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-05-01 | — | — | US | disclosed |
| US-20180086784-A1 | Phosphonate analogs of HIV inhibitor compounds | GILEAD SCIENCES, INC. | 2018-03-29 | — | — | US | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |
| WO-1996033200-A1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED C^¿ESKÉ REPUBLIKY (CZ) | 1996-10-24 | — | — | WO | disclosed |
| WO-1996026933-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1996-09-06 | — | — | WO | disclosed |
| WO-1996023801-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1996-08-08 | — | — | WO | disclosed |
| EP-0719274-A1 | METHOD FOR DOSING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007919-A1 | METHOD FOR DOSING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 1995-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041794-A1 | Nucleotide analogs | PNP, NUDT1, TYMP | ALDH1A1 4101/4885ALOX15 3771/4885HSD17B10 3585/4885 |
| US-20190315785-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | PIK3CA, TYMP, ITPA | ALDH1A1 4577/4885ALOX15 3842/4885HSD17B10 3380/4885 |
| US-20190345190-A1 | PHOSPHONATE ANALOGS OF HIV INHIBITOR COMPOUNDS | PIK3CA, TYMP, ITPA | ALDH1A1 4577/4885ALOX15 3842/4885HSD17B10 3380/4885 |
| US-20180086784-A1 | Phosphonate analogs of HIV inhibitor compounds | PIK3CA, TYMP, ITPA | ALDH1A1 4577/4885ALOX15 3842/4885HSD17B10 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.