Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | RAB9A | P51151 | 4/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.74 |
| ▸ | HPGD | P15428 | 6/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | FHIT | P49789 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143421 | 0.88 | MAPT (1.00) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8198410 | 0.85 | ALDH1A1 (1.00) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL14975641 | 0.85 | ALDH1A1 (1.00) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL7012743 | 0.81 | ALDH1A1 (1.00) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL12082955 | 0.81 | KDM4E (1.00) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3498311 | 0.80 | MAPT (0.77) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL1622309 | 0.80 | FHIT (0.77) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL10508272 | 0.80 | ALDH1A1 (0.79) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL18671041 | 0.79 | MAPT (0.84) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL223094 | 0.79 | ALDH1A1 (1.00) | MAPTRAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |