Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.72 |
| ▸ | HPGD | P15428 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | GAA | P10253 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GRM6 | O15303 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13343389 | 0.87 | FHIT (1.00) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL223094 | 0.84 | ALDH1A1 (1.00) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL1143421 | 0.84 | MAPT (1.00) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL168027 | 0.82 | FHIT (0.61) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL24811161 | 0.82 | FHIT (0.72) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL5119925 | 0.82 | FHIT (0.72) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL1605021 | 0.82 | ALDH1A1 (0.68) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL2773935 | 0.82 | ALDH1A1 (0.68) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL8200637 | 0.82 | FHIT (0.83) | FHITALDH1A1HPGDMAPTGAA | |
| SCHEMBL10710308 | 0.82 | ALDH1A1 (0.68) | FHITALDH1A1HPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4240820-A | Method of regulating the growth of plants | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | claimed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-12559502-B2 | Thieno pyrimidines as ferroportin inhibitors | Global Blood Therapeutics, Inc (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250281465-A1 | MOLECULES THAT ENHANCE EXTRACELLULAR VESICLE RELEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-09-11 | — | — | US | disclosed |
| EP-4514352-A1 | MOLECULES THAT ENHANCE EXTRACELLULAR VESICLE RELEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-03-05 | — | — | EP | disclosed |
| US-12172989-B2 | Histone acetyltransferase (HAT) inhibitor and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2024-12-24 | — | — | US | disclosed |
| WO-2024199524-A1 | COMPOUND AS PKMYT1 INHIBITOR | 江苏星盛新辉医药有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118619968-A | Dihydrothienopyrimidino pyrido indol-4-one derivative and application thereof | 新疆工程学院 | 2024-09-10 | — | — | CN | disclosed |
| US-11932656-B1 | Thieno[2,3-d]pyrimidines as COX-2 inhibitors | King Faisal University (SA) | 2024-03-19 | — | — | US | disclosed |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| US-4670560-A | VASODILATING AGENTS, HYPOTENSIVE AGENTS AND/OR CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |
| EP-0207358-A2 | Growth-promoting agent | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |
| US-4482557-A | 3-Substituted-2-oxo-tetrahydro-pyrrol[1,2-a]pyrimidines having digitalis-like activity | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-11-13 | — | — | US | disclosed |
| US-4367229-A | 3-Substituted-tetrahydro-pyrrolo[1,2-a]pyrimidines and pharmaceutical compositions | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-01-04 | — | — | US | disclosed |
| EP-0004931-B1 | USE OF DERIVATIVES OF FURAN AND THIOPHENE AS PLANT-GROWTH REGULATING AGENTS | BAYER AG (DE) | 1981-08-05 | — | — | EP | disclosed |
| US-4240820-A | Method of regulating the growth of plants | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-23 | — | — | US | disclosed |
| EP-0004931-A2 | Use of derivatives of furan and thiophene as plant-growth regulating agents | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |
| US-4079060-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-14 | — | — | US | disclosed |
| US-3997545-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-12-14 | — | — | US | disclosed |
| US-3951989-A | Thienopyridine-carboxylic acid derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932656-B1 | Thieno[2,3-d]pyrimidines as COX-2 inhibitors | PTGES2, PTGS2, PTGES | FHIT 3834/4885ALDH1A1 776/4885HPGD 26/4885 |
| US-12559502-B2 | Thieno pyrimidines as ferroportin inhibitors | HAMP, TFRC, SLC40A1 | FHIT 4451/4885ALDH1A1 898/4885HPGD 383/4885 |
| US-20250281465-A1 | MOLECULES THAT ENHANCE EXTRACELLULAR VESICLE RELEASE | ORAI1, CHERP, CASR | FHIT 4814/4885ALDH1A1 4183/4885HPGD 2995/4885 |
| US-12172989-B2 | Histone acetyltransferase (HAT) inhibitor and use thereof | EP300, HDAC11, HDAC1 | FHIT 3241/4885ALDH1A1 654/4885HPGD 649/4885 |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | FHIT 3517/4885ALDH1A1 1977/4885HPGD 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.