Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CISD2 | Q8N5K1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722802 | 0.87 | CISD2 (0.60) | MAPTGAAHTTNPC1RAB9A | |
| SCHEMBL9722837 | 0.86 | MAPT (0.51) | MAPTGAANPC1RAB9AHPGD | |
| SCHEMBL9722754 | 0.86 | ALDH1A1 (0.61) | MAPTGAARAB9AHPGDALDH1A1 | |
| SCHEMBL9806950 | 0.78 | CISD2 (0.57) | MAPTGAANPC1RAB9AHPGD | |
| SCHEMBL4224451 | 0.77 | MAPT (0.74) | MAPTGAANPC1RAB9AHPGD | |
| SCHEMBL10891632 | 0.76 | CISD2 (0.55) | MAPTGAAHPGDALDH1A1KDM4E | |
| SCHEMBL6790338 | 0.73 | MAPT (0.69) | MAPTGAANPC1RAB9AHPGD | |
| SCHEMBL13303999 | 0.73 | CISD2 (0.52) | MAPTGAAHPGDALDH1A1KDM4E | |
| SCHEMBL16690704 | 0.73 | GAA (0.54) | MAPTGAAHTTHPGDALDH1A1 | |
| SCHEMBL4776005 | 0.72 | MAPT (1.00) | MAPTGAAHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |