Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PMM2 | O15305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156882 | 0.73 | ELANE (0.38) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL3527744 | 0.72 | ALDH1A1 (0.39) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL27552294 | 0.69 | F10 (0.40) | LMNAALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL16289592 | 0.67 | ALDH1A1 (0.46) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL71339 | 0.67 | HDAC3 (0.62) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL70573 | 0.66 | CA12 (0.60) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL9217734 | 0.66 | SMN1; SMN2 (0.51) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9495325 | 0.66 | LMNA (1.00) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL19142574 | 0.66 | TP53 (0.61) | LMNAMAPK1ALDH1A1KDM4EATM | |
| SCHEMBL7517735 | 0.66 | NCEH1 (0.43) | MAPK1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | claimed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | claimed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |