SCHEMBL70573

SCHEMBL70573

COC(=O)c1c2ccccc2c(C(=O)OC)c2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
CA7 P43166 1/20 0.60
CA9 Q16790 1/20 0.60
CA14 Q9ULX7 1/20 0.60
NR4A2 P43354 4/20 0.58
LMNA P02545 2/20 0.58
MAPK1 P28482 1/20 0.58
TSHR P16473 2/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 2/20 0.51
HPGD P15428 2/20 0.51
NCEH1 Q6PIU2 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CREBBP Q92793 1/20 0.50
STAT3 P40763 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11786743 0.93 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL3194807 0.91 MEN1 (0.60) CA12CA1CA2CA7CA9
SCHEMBL28051400 0.89 NR4A2 (0.50) CA12CA1CA2CA7CA9
SCHEMBL28391493 0.86 SMN1; SMN2 (0.60) CA12CA1CA2CA7CA9
SCHEMBL10559440 0.85 ALDH1A1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL28032836 0.85 MEN1 (0.63) CA12CA1CA2CA7CA9
SCHEMBL30881971 0.85 NR4A2 (0.54) CA12CA1CA2CA7CA9
SCHEMBL30881996 0.85 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL31681884 0.84 LMNA (0.50) CA12CA1CA2CA7CA9
SCHEMBL973740 0.84 NR4A2 (0.58) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4883898-A Chemiluminescent compounds UNIVERSITY OF CHICAGO (US) 1989-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 CA12 1221/4885CA1 550/4885CA2 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.