SCHEMBL9722940

SCHEMBL9722940

O=C(OC(=O)C(Cl)CCl)C(Cl)CCl

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9722944 0.83 NAAA (0.34)
SCHEMBL7662336 0.81
SCHEMBL13433733 0.79 TP53 (0.36) TP53TSHRTDP1
SCHEMBL809340 0.78
SCHEMBL8926650 0.78 TSHR (0.43) TSHRTDP1
SCHEMBL8925212 0.78 HCAR2 (0.38) TSHRTDP1
SCHEMBL11214063 0.76 HTT (0.56)
SCHEMBL7583219 0.76 CYP3A4 (0.38) TSHRTDP1
SCHEMBL3899833 0.74 SOAT1 (0.38) TDP1
SCHEMBL8925081 0.74 ALDH1A1 (0.50) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5092903-A PROCESS FOR DYEING OR PRINTING BLENDS OF CELLULOSIC FIBRE MATERIALS AND SILK WITH DIHALO-PROPIONAMIDO OR HALO-ACRYL AMIDO REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1992-03-03 US disclosed
US-4908436-A Reactive dyes CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed
US-4885360-A FOR CELLULOSE CIBA-GEIGY CORPORATION (US) 1989-12-05 US disclosed
US-4801694-A Triazinyl reactive dyestuffs in which triazinyl group is further substituted with a beta-chloroethylsulfonyl- or vinylsulfonylbutyrylamino moiety CIBA-GEIGY CORPORATION (US) 1989-01-31 US disclosed