Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582021 | 0.73 | HPGD (0.47) | HPGDPARP1KDM5BALDH1A1PDPK1 | |
| SCHEMBL22139858 | 0.71 | HPGD (0.44) | HPGDPARP1KDM4EKDM5BRAB9A | |
| SCHEMBL9723069 | 0.70 | HPGD (0.44) | HPGDPARP1KDM5BALDH1A1PDPK1 | |
| SCHEMBL4231028 | 0.69 | HPGD (0.67) | HPGDHTTPARP1KDM4EKDM5B | |
| SCHEMBL8507626 | 0.69 | HPGD (0.43) | HPGDPARP1KDM5BALDH1A1PDPK1 | |
| SCHEMBL9723032 | 0.69 | HPGD (0.47) | HPGDPARP1KDM5BALDH1A1PDPK1 | |
| SCHEMBL9340305 | 0.69 | HPGD (0.43) | HPGDPARP1KDM4EKDM5BRAB9A | |
| SCHEMBL9723036 | 0.69 | HPGD (0.40) | HPGDPARP1KDM4EKDM5BRAB9A | |
| SCHEMBL9684178 | 0.68 | HPGD (0.42) | HPGDHTTPARP1KDM4EKDM5B | |
| SCHEMBL3028553 | 0.68 | KDM4E (0.59) | HPGDKDM4ENPSR1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104878-A | Insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | disclosed |