Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 3/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723048 | 0.91 | ALPI (0.36) | DDR1ALPIPTGS2NPSR1MEN1 | |
| SCHEMBL9723063 | 0.91 | DDR1 (0.33) | DDR1PTGS2 | |
| SCHEMBL9581826 | 0.90 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL9723075 | 0.86 | ALDH1A1 (0.33) | DDR1ALPIPTGS2NPSR1MEN1 | |
| SCHEMBL9582218 | 0.83 | DDR1 (0.34) | DDR1ALPIPTGS2NPSR1 | |
| SCHEMBL9593933 | 0.83 | DDR1 (0.35) | DDR1ALPIPTGS2NPSR1MEN1 | |
| SCHEMBL9582323 | 0.83 | DDR1 (0.34) | DDR1ALPI | |
| SCHEMBL9592740 | 0.83 | DDR1 (0.34) | DDR1ALPI | |
| SCHEMBL9339481 | 0.83 | GABRA2 (0.36) | NPSR1MEN1KMT2AKDM5BL3MBTL1 | |
| SCHEMBL9723047 | 0.82 | POLB (0.34) | ALPIPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104878-A | Insecticides, miticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-14 | — | — | US | disclosed |
| EP-0396250-A1 | Pyrimidinone derivatives | ZENECA LIMITED (GB) | 1990-11-07 | — | — | EP | disclosed |