Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NMBR | P28336 | 1/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514688 | 0.92 | KDM4E (0.61) | EPHX1MEN1KMT2A | |
| SCHEMBL9514663 | 0.85 | CES2 (0.62) | EPHX1 | |
| SCHEMBL6688137 | 0.81 | SMN1; SMN2 (0.67) | KMT2ASOAT1 | |
| SCHEMBL9513440 | 0.80 | MTNR1A (0.64) | EPHX1MEN1KMT2AMAPT | |
| SCHEMBL9723446 | 0.79 | SOAT1 (0.53) | KMT2ASOAT1SOAT2 | |
| SCHEMBL13480578 | 0.79 | SMN1; SMN2 (0.58) | — | |
| SCHEMBL8321568 | 0.78 | — | — | |
| SCHEMBL17117232 | 0.78 | KMT2A (0.64) | EPHX1KMT2ANPC1RAB9A | |
| SCHEMBL462304 | 0.78 | LPAR1 (0.66) | MEN1KMT2A | |
| SCHEMBL9800920 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | disclosed |
| EP-0344425-A2 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-12-06 | — | — | EP | disclosed |