Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679315 | 0.86 | SOAT2 (0.59) | SOAT2SOAT1L3MBTL1 | |
| SCHEMBL9679311 | 0.86 | SOAT2 (0.59) | SOAT2SOAT1L3MBTL1 | |
| SCHEMBL9681111 | 0.86 | SOAT2 (0.53) | ANPEPSOAT2SOAT1 | |
| SCHEMBL9679677 | 0.85 | SOAT2 (0.57) | SOAT2SOAT1 | |
| SCHEMBL9679723 | 0.85 | SOAT2 (0.57) | PSMB5SOAT2SOAT1 | |
| SCHEMBL9680770 | 0.83 | LMNA (0.62) | PSMB5SOAT2SOAT1L3MBTL1 | |
| SCHEMBL9851026 | 0.80 | CTSL (0.61) | KDM1AALDH1A1 | |
| SCHEMBL9723446 | 0.80 | SOAT1 (0.53) | SOAT2SOAT1 | |
| SCHEMBL9681008 | 0.79 | PSMB5 (0.59) | PSMB5SOAT2SOAT1 | |
| SCHEMBL9678920 | 0.78 | SOAT2 (0.53) | PSMB5SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |