Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723575 | 0.86 | EDNRB (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL9723480 | 0.83 | PPARA (0.48) | ALDH1A1MEN1KMT2AKDM4EPPARA | |
| SCHEMBL9204554 | 0.79 | KMT2A (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL2846596 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL4599256 | 0.78 | MMP8 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL2312705 | 0.78 | MMP8 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL12951609 | 0.78 | MMP8 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL17653672 | 0.75 | MMP8 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL16672673 | 0.75 | MMP8 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 | |
| SCHEMBL27652260 | 0.75 | MMP8 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139563-A | HERBICIDAL COMPOUNDS | SHELL RESEARCH LIMITED (GB) | 1992-08-18 | — | — | US | disclosed |
| EP-0400741-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-12-05 | — | — | EP | disclosed |