Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18972898 | 1.00 | CES2 (0.60) | CES2CES1ACHENPSR1SMN1; SMN2 | |
| SCHEMBL80442 | 1.00 | CES2 (0.60) | CES2CES1ACHENPSR1SMN1; SMN2 | |
| SCHEMBL68051 | 0.92 | CES2 (0.69) | CES2CES1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9723456 | 0.92 | CES2 (0.69) | CES2CES1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30741457 | 0.92 | CES2 (0.69) | CES2CES1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL68050 | 0.92 | CES2 (0.69) | CES2CES1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12399066 | 0.92 | ACHE (0.71) | CES2CES1ACHENPSR1SMN1; SMN2 | |
| SCHEMBL14422430 | 0.86 | CES2 (0.52) | CES2CES1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL69743 | 0.85 | CES2 (0.65) | CES2CES1ACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL69744 | 0.85 | CES2 (0.65) | CES2CES1ACHESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165978-A1 | Composition and A Method For Diagnosing And Treating Bacterial Infection | Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Limited (HK) | 2023-06-01 | — | — | US | disclosed |
| US-20230165978-A1 | Composition and A Method For Diagnosing And Treating Bacterial Infection | Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Limited (HK) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165978-A1 | Composition and A Method For Diagnosing And Treating Bacterial Infection | NOD2, PYCARD, NOD1 | CES2 4258/4885CES1 4764/4885ACHE 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.