Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723517 | 0.88 | KMT2A (0.61) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9723538 | 0.86 | KMT2A (0.60) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL462304 | 0.84 | LPAR1 (0.66) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL8845511 | 0.78 | KMT2A (0.68) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9435674 | 0.78 | KMT2A (0.63) | KMT2ALMNASMN1; SMN2MEN1LPAR1 | |
| SCHEMBL9723445 | 0.78 | LPAR1 (0.52) | KMT2ALMNASMN1; SMN2LPAR1NLRP3 | |
| SCHEMBL9723537 | 0.77 | LMNA (0.54) | KMT2ALMNASMN1; SMN2LPAR1 | |
| SCHEMBL9723518 | 0.77 | LMNA (0.54) | KMT2ALMNALPAR1 | |
| SCHEMBL6429941 | 0.76 | KMT2A (0.65) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9509926 | 0.76 | SOAT1 (0.56) | KMT2ALMNASMN1; SMN2MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153223-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |