Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948937 | 0.71 | EGFR (0.40) | ADRA2AADRA2CADRA1AHRH1SLC6A3 | |
| SCHEMBL28549223 | 0.69 | CYP1A2 (0.42) | LMNATSHRCYP2C19CYP2D6TAAR1 | |
| SCHEMBL8422447 | 0.66 | CYP2C19 (0.53) | ADRA2AADRA2CADRA1AHRH1SLC6A3 | |
| SCHEMBL9325233 | 0.66 | BCL6 (0.49) | LMNAKDM4EMAPK1TSHRCYP2C19 | |
| SCHEMBL12609970 | 0.65 | TSHR (0.64) | ADRA2AADRA2CADRA1AHRH1SLC6A3 | |
| SCHEMBL11551005 | 0.65 | ADRA2A (0.49) | ADRA2AADRA2CADRA1AHRH1SLC6A3 | |
| Ethylbenzene SCHEMBL3682234 | 0.64 | TP53 (0.64) | SLC6A2SMN1; SMN2KDM4ETAAR1CYP1A2 | |
| SCHEMBL29957104 | 0.62 | CXCR1 (0.52) | ADRA2AADRA2CADRA1AHRH1SLC6A3 | |
| SCHEMBL8224031 | 0.62 | ADRA2B (0.43) | ADRA2AADRA2CADRA1AHRH1SLC6A3 | |
| SCHEMBL16628474 | 0.61 | BCL6 (0.41) | LMNASMN1; SMN2KDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164442-A | Polysiloxane, acrylic polymer | SHIN-ETSU CHEMICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | claimed |
| US-5164442-A | Polysiloxane, acrylic polymer | SHIN-ETSU CHEMICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |