Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | FABP2 | P12104 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12884985 | 0.81 | LMNA (0.35) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL12885525 | 0.79 | DGAT1 (0.34) | PPARAKMT2ACYP1A2CYP3A4TSHR | |
| SCHEMBL10665040 | 0.73 | ALDH1A1 (0.42) | CYP2C19CYP1A2ALDH1A1TSHRLMNA | |
| SCHEMBL3372602 | 0.73 | PPARA (0.53) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL3374872 | 0.69 | PPARA (0.44) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL29340480 | 0.69 | ALDH1A1 (0.33) | ALDH1A1TSHRLMNASMN1; SMN2ALOX15 | |
| SCHEMBL31286793 | 0.69 | PPARA (0.58) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5159180 | 0.68 | PPARA (0.52) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL2845481 | 0.67 | PPARA (0.42) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5157805 | 0.67 | PPARA (0.50) | PPARACYP2C19MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139563-A | HERBICIDAL COMPOUNDS | SHELL RESEARCH LIMITED (GB) | 1992-08-18 | — | — | US | disclosed |
| EP-0400741-A1 | Herbicidal compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-12-05 | — | — | EP | disclosed |