Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122023 | 0.96 | TSHR (0.58) | TSHRGAATP53HTTPKM | |
| SCHEMBL2991073 | 0.85 | PKM (0.69) | TSHRGAATP53HTTPKM | |
| SCHEMBL11684253 | 0.83 | TSHR (0.64) | TSHRGAATP53HTTPKM | |
| SCHEMBL9364038 | 0.81 | PKM (0.47) | TSHRGAATP53HTTPKM | |
| SCHEMBL11784525 | 0.77 | GAA (0.57) | TSHRGAATP53HTTKDM4E | |
| SCHEMBL11679735 | 0.73 | GAA (0.56) | TSHRGAATP53HTTPKM | |
| SCHEMBL4881545 | 0.72 | LMNA (0.61) | TSHRGAATP53HTTPKM | |
| SCHEMBL11784513 | 0.71 | NPSR1 (0.60) | TSHRGAATP53HTTKDM4E | |
| SCHEMBL7210502 | 0.71 | ABCB11 (0.64) | TSHRGAATP53HTTKDM4E | |
| SCHEMBL9118263 | 0.70 | NPSR1 (0.59) | TSHRGAATP53HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234847-A | — | — | None | — | — | JP | disclosed |
| JP-H04234847-A | USE OF N-ALKYLATED 1,4-DIHYDROPYRIDINE DICARBOXYLATES AS MEDICINE, NEW COMPOUND AND THEIR PRODUCTION | BAYER AG | 1992-08-24 | — | — | JP | disclosed |