SCHEMBL972363

SCHEMBL972363

CCSCCOCCOC

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28377771 1.00 MEN1 (0.39) MEN1KMT2ATDP1CA2ALDH1A1
SCHEMBL974251 1.00 MEN1 (0.39) MEN1KMT2ATDP1CA2ALDH1A1
SCHEMBL13952077 0.98 MEN1 (0.38) MEN1KMT2ATDP1CA2
SCHEMBL11525095 0.89 MEN1 (0.44) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL27751669 0.87 CA2 (0.35) CA2
SCHEMBL5445934 0.87 MEN1 (0.46) MEN1KMT2ATDP1ALDH1A1CYP3A4
SCHEMBL17225877 0.86 TSHR (0.35) MEN1KMT2ATDP1CA2CYP3A4
SCHEMBL247006 0.84
SCHEMBL15593320 0.79
SCHEMBL8940399 0.78 MEN1 (0.52) MEN1KMT2ATDP1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170101445-A1 NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION S&T GLOBAL INC. 2017-04-13 US disclosed
EP-1842250-B1 ELECTRIC CURRENT-PRODUCING DEVICE HAVING A SULFONE-BASED ELECTROLYTE UNIV ARIZONA (US) 2013-09-04 EP disclosed
US-20110020712-A1 ELECTRIC CURRENT-PRODUCING DEVICE HAVING SULFONE-BASED ELECTROLYTE ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2011-01-27 US disclosed
US-7833666-B2 Electric current-producing device having sulfone-based electrolyte Arizona Board of Regents for and behalf of Arizona State University (US) 2010-11-16 US disclosed
US-20070298326-A1 Electric Current-Producing Device Having Sulfone-Based Electrolyte UNITED STATES DEPARTMENT OF ENERGY 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170101445-A1 NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION HAVCR2, TSLP, HLA-DRB1 MEN1 2078/4885KMT2A 4455/4885TDP1 3894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.